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Turbocharging Protein Binding Site Prediction with Geometric Attention, Inter-resolution Transfer Learning, and Homology-Based Augmentation

Protein binding sites are the critical regions on a protein's surface where it interacts with other molecules, such as DNA, RNA, or small ligands. Understanding these binding sites is fundamental to numerous applications in biology and medicine, from drug discovery to understanding disease mechanisms. However, predicting these binding sites accurately remains challenging due to protein…

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Gasdermin D: The Unsung Hero in Tissue Repair and Metabolic Crosstalk

The human body is a remarkable machine capable of healing and regenerating tissues after injury. But what drives this incredible ability to repair itself? Recent research has uncovered a fascinating connection between inflammation, metabolism, and tissue repair, with a protein called Gasdermin D (GSDMD) playing a pivotal role. This blog will explore how Gasdermin D-mediated…

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Paracetamol to Pan D: Check Complete List of Drugs That Failed CDSCO’s Quality Test

Overview India's Central Drugs Standards Control Organization (CDSCO) recently issued a drug quality alert that has raised concerns about the safety and quality of several commonly used medicines. Fifty-three medicines, including popular paracetamol, calcium, and vitamin D3 supplements, failed the CDSCO's quality test. These findings are part of the CDSCO's 'Not of Standard Quality' (NSQ)…

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